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Combined Nivolumab and Ipilimumab in Melanoma Metastatic to the Brain
NEJM 379:722-730,789, Tawbi, H.A.,et al, 2018
See this aricle in Pubmed

Article Abstract
Nivolumab combined with ipilimumab had clinically meaningful intracranial efficacy, concordant with extracranial activity, in patients with melanoma who had untreated brain metastases.
 
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efficacy
immune checkpoint inhibitors
immunotherapy
ipilimumab
melanoma,malignant
neoplasm,metastatic to CNS
neoplasm,metastatic to CNS-treatment of
nivolumab
safety
treatment of neurologic disorder

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